GLASS EXPANSION
Quality By Design
Glass Expansion Newsletter Issue 19 – page 1
Glass Expansion Newsletter • June 2009 • issue 19
Application Spotlight
Advancing Quality Control
in ICP Spectrometry
Introduction
Both inductively coupled
plasma optical emission
spectrometry (ICP-OES)
and inductively coupled
plasma mass spectrometry
(ICP-MS) have become
workhorses in today’s
inorganic laboratories.
Most parameters of the
spectrometer are tightly
controlled and easy to
monitor. For example, the
detectors employed are
often temperature controlled.
Gases used are pressure
and/or flow regulated.
The RF power supply has
a built-in feedback loop,
etc. However, there are
two areas of the sample
Key Events
JAIMA Show
2009
A full range of Glass
Expansion products will be
on display at the JAIMA
Show, Tokyo, Japan,
September 2 to 4, 2009
and Glass Expansion
specialists will be on hand
to assist you.
ICASS
Conference
2009
Glass Expansion is
sponsoring the atomic
spectroscopy symposium
at the ICASS conference
in Kingston, Ontario,
Canada, August 9-12,
2009. Jerry Dulude of
our US office will be
presenting a paper in that
session entitled, “The
Effect of Spray Chamber
Temperature Control on
Environmental Analyses
by ICP”
GE News
New 2009
Catalog
If you do not yet have your
copy of the 2009 Glass
Expansion catalog, please
send your mailing address
to enquiries@geicp.com and
we will send you a copy
immediately.
Continued on
page 7
nebulizer
sample
capillary
tube
spray chamber torch RF coil
pump tubing
peristaltic pump
In this Issue
Application Spotlight 1
Key Events 1
New Products 4-6
U-series nebulizer
D-Torch for PerkinElmer Optima 2/4/5/7000DV
Ceramic VeeSpray nebulizer
Instrument news 5-6
From Agilent Technologies
From PerkinElmer
From Spectro
From Thermo Fisher Scientific
From Varian
autosampler
introduction system
where recent advances
have enhanced the
control of quality for these
spectrometers and these
are the subject of this article.
Figure 1 is a schematic of
the ICP sample introduction
system. The sampler
sampler
cone
skimmer
cone
autosampler
probe
and skimmer cones are
present only for the ICPMS,
otherwise the sample
introduction systems for
ICP-OES and ICP-MS are in
essence the same.
Sample Uptake
Rate
Sample is delivered to the
nebulizer of the sample
introduction system typically
via a peristaltic pump.
The operator chooses the
appropriate pump tubing
internal diameter and
pump speed to achieve the
desired sample flow rate.
This is typically between
1 and 2 mL/min for ICPOES
and somewhat lower
for ICP-MS. In order to
achieve the best analytical
performance, sample
delivery must be consistent
over both the short and long
term. Failure to consistently
deliver sample shows up
in terms of poor precision
and inaccuracy but may
not become evident until a
QC sample is measured.
1
Figure 1 - Schematic of a typical sample introduction system for an ICP spectrometer.
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